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Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus

The matrix protein (M) of paramyxoviruses plays a key role in determining virion morphology by directing viral assembly and budding. Here, we report the crystal structure of the human metapneumovirus M at 2.8 Å resolution in its native dimeric state. The structure reveals the presence of a high-affi...

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Detalhes bibliográficos
Main Authors: Leyrat, Cedric, Renner, Max, Harlos, Karl, Huiskonen, Juha T., Grimes, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887258/
https://ncbi.nlm.nih.gov/pubmed/24316400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.10.013
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