Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man

Understanding transcriptional regulation of pancreatic development is required to advance current efforts in developing beta cell replacement therapies for patients with diabetes. Current knowledge of key transcriptional regulators has predominantly come from mouse studies, with rare, naturally occu...

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Bibliografski detalji
Glavni autori: Flanagan, Sarah E., De Franco, Elisa, Lango Allen, Hana, Zerah, Michele, Abdul-Rasoul, Majedah M., Edge, Julie A., Stewart, Helen, Alamiri, Elham, Hussain, Khalid, Wallis, Sam, de Vries, Liat, Rubio-Cabezas, Oscar, Houghton, Jayne A.L., Edghill, Emma L., Patch, Ann-Marie, Ellard, Sian, Hattersley, Andrew T.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2014
Teme:
Short Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887257/
https://ncbi.nlm.nih.gov/pubmed/24411943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.11.021
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