Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

In order to test the suggestion that antipsychotic drugs act by blocking dopamine receptors in the brain, the direct effects of such neuroleptic drugs were tested on the stereospecific binding of [3H]dopamine and of [3H]haloperidol to rat brain striata and their subfractions. The stereospecific comp...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Seeman, P, Chau-Wong, M, Tedesco, J, Wong, K
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1975
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1060115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.11.4376
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