Downregulation of Calcineurin Gene Is Associated with Glucantime(®) Resiatance in Leishmania infantum

BACKGROUND: Pentavalent antimonials are the first line drugs for the treatment of leishmaniasis. Unresponsiveness of Leishmania spp. to antimonial drugs is a serious problem in some endemic areas. Investigations on molecular mechanisms involved in drug resistance are essential for monitoring and man...

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Hlavní autoři: Bagher KHADEM ERFAN, Mohammad, MOHEBALI, Mehdi, KAZEMI-RAD, Elham, HAJJARAN, Homa, EDRISSIAN, GholamHossein, MAMISHI, Setareh, SAFFARi, Mojtaba, RAOOFIAN, Reza, HEIDARI, Mansour
Médium: Artigo
Jazyk:Inglês
Vydáno: Tehran University of Medical Sciences 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887235/
https://ncbi.nlm.nih.gov/pubmed/24454427
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