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Identification of a region in 23S rRNA located at the peptidyl transferase center.

A photolyzable derivative of dipeptidyl-tRNA, p-azido-N-tBoc-Phe-[3H]Phe-tRNA, bound reversibly to 70S ribosomes in the presence of poly(U), becomes, when irradiated, covalently attached to components of the 50S ribosomal subunit. Most of the reaction occurs within the 23S RNA, while ribosomal prote...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sonenberg, N, Wilchek, M, Zamir, A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1975
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1105580/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.11.4332
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