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APOE Genotype Modulates Proton Magnetic Resonance Spectroscopy Metabolites in the Aging Brain

BACKGROUND: Proton magnetic resonance spectroscopy ((1)H-MRS) studies on healthy aging have reported inconsistent findings and have not systematically taken into account the possible modulatory effect of APOE genotype. We aimed to quantify brain metabolite changes in healthy subjects in relation to...

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Détails bibliographiques
Auteurs principaux: Gomar, Jesus J., Gordon, Marc L., Dickinson, Dwight, Kingsley, Peter B., Uluğ, Aziz M., Keehlisen, Lynda, Huet, Sarah, Buthorn, Justin J., Koppel, Jeremy, Christen, Erica, Conejero-Goldberg, Concepcion, Davies, Peter, Goldberg, Terry E.
Format: Artigo
Langue:Inglês
Publié: 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887136/
https://ncbi.nlm.nih.gov/pubmed/23831342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.05.022
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