Bioassay-Guided Fractionation of Extracts from Codiaeum variegatum against Entamoeba histolytica Discovers Compounds That Modify Expression of Ceramide Biosynthesis Related Genes

Leaves of Codiaeum variegatum (“garden croton”) are used against bloody diarrhoea by local populations in Cameroon. This study aims to search for the active components from C. variegatum against Entamoeba histolytica, and thereby initiate the study of their mechanism of action. A bioassay-guided scr...

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Detalhes bibliográficos
Main Authors: Mfotie Njoya, Emmanuel, Weber, Christian, Hernandez-Cuevas, Nora Adriana, Hon, Chung-Chau, Janin, Yves, Kamini, Melanie F. G., Moundipa, Paul F., Guillén, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887121/
https://ncbi.nlm.nih.gov/pubmed/24416462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002607
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