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Cell Tropism Predicts Long-term Nucleotide Substitution Rates of Mammalian RNA Viruses

The high rates of RNA virus evolution are generally attributed to replication with error-prone RNA-dependent RNA polymerases. However, these long-term nucleotide substitution rates span three orders of magnitude and do not correlate well with mutation rates or selection pressures. This substitution...

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Bibliografiske detaljer
Main Authors: Hicks, Allison L., Duffy, Siobain
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887100/
https://ncbi.nlm.nih.gov/pubmed/24415935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003838
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