FOXL2, GATA4, and SMAD3 Co-Operatively Modulate Gene Expression, Cell Viability and Apoptosis in Ovarian Granulosa Cell Tumor Cells

Aberrant ovarian granulosa cell proliferation and apoptosis may lead to granulosa cell tumors (GCT), the pathogenesis of which involves transcription factors GATA4, FOXL2, and SMAD3. FOXL2 gene harbors a point mutation (C134W) in a vast majority of GCTs. GATA4 is abundantly expressed in GCTs and its...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Anttonen, Mikko, Pihlajoki, Marjut, Andersson, Noora, Georges, Adrien, L'Hôte, David, Vattulainen, Sanna, Färkkilä, Anniina, Unkila-Kallio, Leila, Veitia, Reiner A., Heikinheimo, Markku
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887065/
https://ncbi.nlm.nih.gov/pubmed/24416423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085545
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados