Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis

Muscle-specific kinase (MuSK) belongs to the nicotinic acetylcholine receptor complex which is targeted by pathogenic autoantibodies causing Myasthenia gravis. While up to 95% of patients with generalized Myasthenia gravis were shown to be positive for acetylcholine receptor-specific autoantibodies,...

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Main Authors: George, Sandra, Paulick, Silvia, Knütter, Ilka, Röber, Nadja, Hiemann, Rico, Roggenbuck, Dirk, Conrad, Karsten, Küpper, Jan-Heiner
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886972/
https://ncbi.nlm.nih.gov/pubmed/24416182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083924
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