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p53 and TAp63 Promote Keratinocyte Proliferation and Differentiation in Breeding Tubercles of the Zebrafish

p63 is a multi-isoform member of the p53 family of transcription factors. There is compelling genetic evidence that ΔNp63 isoforms are needed for keratinocyte proliferation and stemness in the developing vertebrate epidermis. However, the role of TAp63 isoforms is not fully understood, and TAp63 kno...

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Détails bibliographiques
Auteurs principaux: Fischer, Boris, Metzger, Manuel, Richardson, Rebecca, Knyphausen, Philipp, Ramezani, Thomas, Franzen, Rainer, Schmelzer, Elmon, Bloch, Wilhelm, Carney, Thomas J., Hammerschmidt, Matthias
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886889/
https://ncbi.nlm.nih.gov/pubmed/24415949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004048
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