7α-hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier

There is a continuous flux of the oxysterol 27-hydroxycholesterol (27-OHC) from the circulation across the blood-brain barrier (BBB) into the brain. The major metabolite of 27-OHC in the brain is 7α-hydroxy-3-oxo-4-cholestenoic acid (7-HOCA). We confirm a recent report describing the presence of thi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Saeed, Ahmed, Floris, Federico, Andersson, Ulla, Pikuleva, Irina, Lövgren-Sandblom, Anita, Bjerke, Maria, Paucar, Martin, Wallin, Anders, Svenningsson, Per, Björkhem, Ingemar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Patient-Oriented and Epidemiological Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886670/
https://ncbi.nlm.nih.gov/pubmed/24319290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P044982
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