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Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1

Accumulation of foam cells in the neointima represents a key event in atherosclerosis. We previously demonstrated that Tanshinone IIA (Tan), a lipophilic bioactive compound extracted from Salvia miltiorrhiza Bunge, inhibits experimental atherogenesis, yet the detailed mechanisms are not fully unders...

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Main Authors: Liu, Zhiping, Wang, Jiaojiao, Huang, Erwen, Gao, Si, Li, Hong, Lu, Jing, Tian, Kunming, Little, Peter J., Shen, Xiaoyan, Xu, Suowen, Liu, Peiqing
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Biochemistry and Molecular Biology 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886659/
https://ncbi.nlm.nih.gov/pubmed/24302760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M040394
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