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Sequence effects in the melting and renaturation of short DNA oligonucleotides: structure and mechanistic pathways

The renaturation/denaturation of DNA oligonucleotides is characterized in the context of expanded ensemble (EXE) and Transition Path Sampling (TPS) simulations. Free energy profiles have been determined from EXE for DNA sequences of varying composition, chain length, and ionic strength. TPS simulati...

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Bibliografiske detaljer
Main Authors: Sambriski, E. J., Ortiz, V., de Pablo, J. J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886633/
https://ncbi.nlm.nih.gov/pubmed/21817250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0953-8984/21/3/034105
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