Estimates of the pharmacokinetics of famciclovir and its active metabolite penciclovir in young Asian elephants (Elephas maximus)

OBJECTIVE: To determine plasma pharmacokinetics of penciclovir following oral and rectal administration of famciclovir to young Asian elephants (Elephas maximus). ANIMALS: 6 healthy Asian elephants (5 females and 1 male), 4.5 to 9 years old and weighing 1,646 to 2,438 kg. PROCEDURES: Famciclovir was...

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Bibliographische Detailangaben
Hauptverfasser: Brock, A. Paige, Isaza, Ramiro, Hunter, Robert P., Richman, Laura K., Montali, Richard J., Schmitt, Dennis L., Koch, David E., Lindsay, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886626/
https://ncbi.nlm.nih.gov/pubmed/23176429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2460/ajvr.73.12.1996
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