Poly(ADP-Ribose): Release of Template Restriction in HeLa Cells

Evidence is presented to show that ADP-ribosylation of nuclear proteins by poly(ADP-ribose) polymerase enhances template-primer activity of HeLa cell nuclear DNA. We used Escherichia coli DNA polymerase I (EC 2.7.7.7; DNA nucleotidyltransferase) as an exogenous probe of nuclear DNA status. Neither N...

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Bibliographic Details
Main Authors: Roberts, Jerry H., Stark, Patricia, Smulson, Mark
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Biological Sciences: Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC388653/
https://ncbi.nlm.nih.gov/pubmed/4370271
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