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Failure of Lymphocytes to Reexpress Antigen Receptors after Brief Interaction with a Tolerogenic D-Amino Acid Copolymer

We present data concerning a strongly tolerogenic molecule made of a copolymer of D-amino acids that is not metabolizable poly(D-glutamic acid-D-lysine). The dinitrophenyl conjugate of this molecule induces profound tolerance in dinitrophenyl-specific B lymphocytes both in vivo and in vitro. We show...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ault, Kenneth A., Unanue, Emil R., Katz, David H., Benacerraf, Baruj
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
Fag:
Biological Sciences: Immunology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4547208/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.8.3111
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