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Requirement of 3′-Terminal Poly(adenylic acid) for the Infectivity of Poliovirus RNA

Ribonuclease H (EC 3.1.4.34) has been used to remove selectively much of the 3′-terminal poly(adenylic acid) [poly(A)] from poliovirus RNA by treating the RNA with the enzyme in the presence of poly(dT). Over 80% of the poly(A) could be removed and the residuum was found as oligo(A) stretches attach...

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Detalhes bibliográficos
Main Authors: Spector, Deborah H., Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388603/
https://ncbi.nlm.nih.gov/pubmed/4370340
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