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Homozygous inactivation of the Lgi1 gene results in hypomyelination in the peripheral and central nervous system
Mutations in the LGI1 gene in humans predispose to the development of Autosomal Dominant Partial Epilepsy with Auditory Features (ADPEAF). Homozygous inactivation of the Lgi1 gene in mice results in an epilepsy phenotype characterized by clonic seizures within 2–3 weeks after birth. Before onset of...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885985/ https://ncbi.nlm.nih.gov/pubmed/20857514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22496 |
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