Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes

Simvastatin, a HMG-CoA reductase inhibitor, is prescribed worldwide to patients with hypercholesterolemia. Although simvastatin is well tolerated, side effects like myotoxicity are reported. The mechanism for statin-induced myotoxicity is still poorly understood. Reports have suggested impaired mito...

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Autors principals: Smith, Robert, Solberg, Rigmor, Jacobsen, Linn Løkken, Voreland, Anette Larsen, Rustan, Arild Christian, Thoresen, G. Hege, Johansen, Harald Thidemann
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885717/
https://ncbi.nlm.nih.gov/pubmed/24416446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085721
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