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Atypical heterochromatin organization and replication are rapidly acquired by somatic cells following fusion-mediated reprogramming by mouse ESCs

We recently reported that mouse embryonic stem cells (ESCs) in S/G(2) are more efficient at reprogramming somatic cells than ESCs at other stages of the cell cycle. We also provided evidence that DNA replication is induced in the nuclei of somatic partners upon fusion with ESC partners, and showed t...

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Detalhes bibliográficos
Main Authors: Brown, Karen E, Bagci, Hakan, Soza-Ried, Jorge, Fisher, Amanda G
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885636/
https://ncbi.nlm.nih.gov/pubmed/24036550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26223
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