4-Phenylbutyrate Inhibits Tunicamycin-Induced Acute Kidney Injury via CHOP/GADD153 Repression

Different forms of acute kidney injury (AKI) have been associated with endoplasmic reticulum (ER) stress; these include AKI caused by acetaminophen, antibiotics, cisplatin, and radiocontrast. Tunicamycin (TM) is a nucleoside antibiotic known to induce ER stress and is a commonly used inducer of AKI....

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Detalhes bibliográficos
Main Authors: Carlisle, Rachel E., Brimble, Elise, Werner, Kaitlyn E., Cruz, Gaile L., Ask, Kjetil, Ingram, Alistair J., Dickhout, Jeffrey G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885586/
https://ncbi.nlm.nih.gov/pubmed/24416259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084663
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