Overexpression of HIF-1α, metallothionein and SLUG is associated with high TNM stage and lymph node metastasis in papillary thyroid carcinoma

Hypoxia inducible factor-1α (HIF-1α) is upregulated by hypoxia, and involved in tumor growth and metastasis in many malignant tumors including papillary thyroid carcinoma (PTC). Metallothionein (MT) is a group of small molecular weight cysteine-rich proteins with a broad variety of functions. SLUG i...

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Hlavní autoři: Wang, Ni, Dong, Chao-Ran, Jiang, Rong, Tang, Cui, Yang, Lei, Jiang, Qi-Feng, Chen, George G, Liu, Zhi-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885487/
https://ncbi.nlm.nih.gov/pubmed/24427353
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