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PknE, a Serine/Threonine Protein Kinase of Mycobacterium tuberculosis Initiates Survival Crosstalk That Also Impacts HIV Coinfection

Serine threonine protein kinases (STPK) play a major role in the pathogenesis of Mycobacterium tuberculosis. Here, we examined the role of STPK pknE, using a deletion mutant ΔpknE in the modulation of intracellular signaling events that favor M. tuberculosis survival. Phosphorylation kinetics of MAP...

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Detalhes bibliográficos
Main Authors: Parandhaman, Dinesh Kumar, Hanna, Luke Elizabeth, Narayanan, Sujatha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885422/
https://ncbi.nlm.nih.gov/pubmed/24421891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083541
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