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Establishment of a Tetraploid, Immunoglobulin-Producing Cell Line from the Hybridization of Two Human Lymphocyte Lines

We here report the establishment of a seemingly permanent hybrid cell line formed by fusion of the cells of two biochemically mutant human lymphocyte lines. One parental line (UM-1-6TGr) was deficient in hypoxanthine-guanine phosphoribosyl transferase (IMP: pyrophosphate phosphoribosyltransferase, E...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bloom, Arthur D., Nakamura, Frank T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4368696/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.7.2689
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