Gene Expression Profiles of Peripheral Blood Mononuclear Cells Reveal Transcriptional Signatures as Novel Biomarkers for Cardiac Remodeling in Rats with Aldosteronism and Hypertensive Heart Disease

OBJECTIVES: In searching for a noninvasive surrogate tissue having mimicry with the prooxidant/-proinflammatory hypertensive heart disease (HHD) phenotype, we turned to peripheral blood mononuclear cells (PBMC). We tested whether iterations in [Ca(2+)](i), [Zn(2+)](i) and oxidative stress in cardiom...

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Hlavní autoři: Gerling, Ivan C., Ahokas, Robert A., Kamalov, German, Zhao, Wenyuan, Bhattacharya, Syamal K., Sun, Yao, Weber, Karl T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885325/
https://ncbi.nlm.nih.gov/pubmed/24416716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchf.2013.09.003
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