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Expression of Purine Overproduction in a Series of 8-Azaguanine-Resistant Diploid Human Lymphoblast Lines

For study of the basis of an X-linked form of gout in man, several clonal lines deficient in hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) were selected from the human lymphoblast line WI-L2 by spontaneous and mutagen-induced resistance to 10 μM 8-azaguanine. Three groups could be defi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lever, Julia E., Nuki, George, Seegmiller, J. Edwin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1974
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC388531/
https://ncbi.nlm.nih.gov/pubmed/4527800
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