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p53-dependent delayed effects of radiation vary according to time of irradiation of p53 (+ / −) mice

We previously reported that in p53 (+ / −) mice that had been given a whole-body dose of 3 Gy at 8 weeks of age, p53-dependent delayed effects of radiation, as manifested in T-cell receptor (TCR) variant fractions (VF) instability in mouse splenocytes, were biphasic, namely, induction of TCR-VF muta...

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Autori principali: Okazaki, Ryuji, Ootsuyama, Akira
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885116/
https://ncbi.nlm.nih.gov/pubmed/23764457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrt083
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