Sevoflurane Preconditioning Attenuates Myocardial Ischemia/Reperfusion Injury via Cav-3-Dependent COX-2 Inhibition

BACKGROUND: The inhaled anesthetic sevoflurane has been demonstrated to protect against myocardial ischemia/reperfusion (MI/R) injury, via mechanisms involving AMP-activated protein kinase (AMPK) and caveolin-3 (Cav-3). However, the relative contributions of AMPK and Cav-3 to sevoflurane preconditio...

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Hauptverfasser: Zhao, Jianli, Zhang, Yanqing, Wang, Feng, Jiao, Liyuan, Lau, Wayne Bond, Wang, Lili, Liu, Baojiang, Gao, Erhe, Koch, Walter J., Ma, Xin-Liang, Wang, Yajing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884906/
https://ncbi.nlm.nih.gov/pubmed/24030395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.000045
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