Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6

The eukaryotic exosome exoribonuclease Rrp6 forms a complex with Rrp47 that functions in nuclear RNA quality control mechanisms, the degradation of cryptic unstable transcripts (CUTs), and in the 3′ end maturation of stable RNAs. Stable expression of Rrp47 is dependent upon its interaction with the...

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Bibliographic Details
Main Authors: Garland, William, Feigenbutz, Monika, Turner, Martin, Mitchell, Phil
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884647/
https://ncbi.nlm.nih.gov/pubmed/24106327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039388.113
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