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Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6

The eukaryotic exosome exoribonuclease Rrp6 forms a complex with Rrp47 that functions in nuclear RNA quality control mechanisms, the degradation of cryptic unstable transcripts (CUTs), and in the 3′ end maturation of stable RNAs. Stable expression of Rrp47 is dependent upon its interaction with the...

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Detalhes bibliográficos
Main Authors: Garland, William, Feigenbutz, Monika, Turner, Martin, Mitchell, Phil
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884647/
https://ncbi.nlm.nih.gov/pubmed/24106327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039388.113
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