Photoaffinity Labeling of the Ouabain-Binding Site on (Na(+) + K(+)) Adenosinetriphosphatase
An ethyl diazomalonyl derivative of cymarin was synthesized in order to photoaffinity label the cardiac glycoside-binding site on (Na(+) + K(+)) adenosinetriphosphate (EC 3.6.1.3). When a noncovalent complex of the enzyme and this cardiac glycoside derivative was photolyzed, a covalent bond was form...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1974
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4276295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2352 |
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