Tumor Evolution and Intratumor Heterogeneity of an Oropharyngeal Squamous Cell Carcinoma Revealed by Whole-Genome Sequencing

Head and neck squamous cell carcinoma (HNSCC) is characterized by significant genomic instability that could lead to clonal diversity. Intratumor clonal heterogeneity has been proposed as a major attribute underlying tumor evolution, progression, and resistance to chemotherapy and radiation. Underst...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Xinyi Cindy, Xu, Chang, Mitchell, Ryan M, Zhang, Bo, Zhao, Derek, Li, Yao, Huang, Xin, Fan, Wenhong, Wang, Hongwei, Lerma, Luisa Angelica, Upton, Melissa P, Hay, Ashley, Méndez, Eduardo, Zhao, Lue Ping
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884528/
https://ncbi.nlm.nih.gov/pubmed/24403859
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