Tumor Evolution and Intratumor Heterogeneity of an Oropharyngeal Squamous Cell Carcinoma Revealed by Whole-Genome Sequencing

Head and neck squamous cell carcinoma (HNSCC) is characterized by significant genomic instability that could lead to clonal diversity. Intratumor clonal heterogeneity has been proposed as a major attribute underlying tumor evolution, progression, and resistance to chemotherapy and radiation. Underst...

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Detalhes bibliográficos
Main Authors: Zhang, Xinyi Cindy, Xu, Chang, Mitchell, Ryan M, Zhang, Bo, Zhao, Derek, Li, Yao, Huang, Xin, Fan, Wenhong, Wang, Hongwei, Lerma, Luisa Angelica, Upton, Melissa P, Hay, Ashley, Méndez, Eduardo, Zhao, Lue Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884528/
https://ncbi.nlm.nih.gov/pubmed/24403859
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