Quantitative Analysis of [(11)C]-Erlotinib PET Demonstrates Specific Binding for Activating Mutations of the EGFR Kinase Domain

Activating mutations of the epidermal growth factor receptor (EGFR) occur in multiple tumor types, including non-small cell lung cancer (NSCLC) and malignant glioma, and have become targets for therapeutic intervention. The determination of EGFR mutation status using a noninvasive, molecular imaging...

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Detalhes bibliográficos
Main Authors: Petrulli, J Ryan, Sullivan, Jenna M, Zheng, Ming-Qiang, Bennett, Daniel C, Charest, Jonathan, Huang, Yiyun, Morris, Evan D, Contessa, Joseph N
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884525/
https://ncbi.nlm.nih.gov/pubmed/24403856
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