Dominance of the Senescent Phenotype in Heterokaryons Between Replicative and Post-Replicative Human Fibroblast-Like Cells

In heterokaryons between senescent and young diploid fibroblast-like cells, dominance of the former with respect to nuclear DNA synthesis (incorporation of [(3)H]thymidine) was demonstrated. For identification of the respective partners, double-layer autoradiography was used after the old cells were...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Norwood, Thomas H., Pendergrass, William R., Sprague, Curtis A., Martin, George M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
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Biological Sciences: Genetics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388425/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4366757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2231
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