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Noncovalent Modification of Deoxyhemoglobin S Solubility and Erythrocyte Sickling

Ammonium sulfate, as well as potassium phosphate, can be used to measure solubility differences between hemoglobin S and hemoglobin A. In addation, the solubility of deoxyhemoglobin C(Harlem) in 1.96 M phosphate has a markedly different temperature dependence from that of deoxyhemoglobin S. This obs...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Waterman, Michael R., Yamaoka, Kotaro, Dahm, Larry, Taylor, Joe, Cottam, G. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388423/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4526343/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2222
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