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Effect of Insulin on Sterol and Fatty Acid Synthesis and Hydroxymethylglutaryl CoA Reductase Activity in Mammalian Cells Grown in Culture

The effects of insulin on the synthesis of sterols and fatty acids and on the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (EC 1.1.1.34), a rate-limiting enzyme for sterol synthesis, were studied in mammalian cells grown in culture. While in some established cell lines sterol synthesi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bhathena, Sam J., Avigan, Joel, Schreiner, Marta E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4526203/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2174
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