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Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

To assess the role of transcriptional enhancers in regulating accessibility of the T-cell receptor beta-chain (TCRbeta) locus, we generated embryonic stem cell lines in which a single allelic copy of the endogenous TCRbeta enhancer (Ebeta) was either deleted or replaced with the immunoglobulin heavy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bories, J C, Demengeot, J, Davidson, L, Alt, F W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC38841/
https://ncbi.nlm.nih.gov/pubmed/8755569
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