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Protein Domains of Unknown Function Are Essential in Bacteria

More than 20% of all protein domains are currently annotated as “domains of unknown function” (DUFs). About 2,700 DUFs are found in bacteria compared with just over 1,500 in eukaryotes. Over 800 DUFs are shared between bacteria and eukaryotes, and about 300 of these are also present in archaea. A to...

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Bibliographic Details
Main Authors: Goodacre, Norman F., Gerloff, Dietlind L., Uetz, Peter
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884060/
https://ncbi.nlm.nih.gov/pubmed/24381303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00744-13
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