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Homoharringtonine and omacetaxine for myeloid hematological malignancies

Homoharringtonine (HHT), a plant alkaloid with antitumor properties originally identified nearly 40 years ago, has a unique mechanism of action by preventing the initial elongation step of protein synthesis. HHT has been used widely in China for the treatment of chronic myeloid leukemia (CML), acute...

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Bibliografske podrobnosti
Main Authors: Lü, Shuqing, Wang, Jianmin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884015/
https://ncbi.nlm.nih.gov/pubmed/24387717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-2
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