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Nerve growth factor/p75 neurotrophin receptor–mediated sensitization of rat sensory neurons depends on membrane cholesterol

Nerve growth factor (NGF) is an important mediator in the initiation of the inflammatory response and NGF via activation of the p75 neurotrophin receptor (p75(NTR)) and downstream sphingomyelin signaling leads to significant enhancement of the excitability of small diameter sensory neurons. Because...

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Détails bibliographiques
Auteurs principaux: Zhang, Y.H., Khanna, R., Nicol, G.D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883999/
https://ncbi.nlm.nih.gov/pubmed/23811397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.06.039
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