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Nerve growth factor/p75 neurotrophin receptor–mediated sensitization of rat sensory neurons depends on membrane cholesterol

Nerve growth factor (NGF) is an important mediator in the initiation of the inflammatory response and NGF via activation of the p75 neurotrophin receptor (p75(NTR)) and downstream sphingomyelin signaling leads to significant enhancement of the excitability of small diameter sensory neurons. Because...

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Main Authors: Zhang, Y.H., Khanna, R., Nicol, G.D.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883999/
https://ncbi.nlm.nih.gov/pubmed/23811397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.06.039
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