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MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A
Hormone-sensitive prostate cancer typically progresses to castration resistant prostate cancer (CRPC) after the androgen deprivation therapy. We investigated the impact of microRNAs (miRs) in the transition of prostate cancer to CRPC. MiR-221/-222 was highly expressed in bone metastatic CRPC tumor s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883998/ https://ncbi.nlm.nih.gov/pubmed/23770851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.230 |
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