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Adoption of the Q transcriptional regulatory system for zebrafish transgenesis
The Gal4-UAS regulatory system of yeast is widely used to modulate gene expression in Drosophila; however, there are limitations to its usefulness in transgenic zebrafish, owing to progressive methylation and silencing of the CpG-rich multicopy upstream activation sequence. Although a modified, less...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883888/ https://ncbi.nlm.nih.gov/pubmed/23792917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.06.012 |
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