Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: Distinct roles of superoxide anion and superoxide dismutases

The loss of dopaminergic neurons induced by the parkinsonian toxins paraquat, rotenone and 1-methyl-4-phenylpyridinium (MPP(+)) is associated with oxidative stress. However, controversial reports exist regarding the source/compartmentalization of reactive oxygen species (ROS) generation and its exac...

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Main Authors: Rodriguez-Rocha, Humberto, Garcia-Garcia, Aracely, Pickett, Chillian, Sumin, Li, Jones, Jocelyn, Chen, Han, Webb, Brian, Choi, Jae, Zhou, You, Zimmerman, Matthew C., Franco, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883883/
https://ncbi.nlm.nih.gov/pubmed/23602909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.04.021
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