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Pirfenidone inhibits migration, differentiation, and proliferation of human retinal pigment epithelial cells in vitro

PURPOSE: To investigate the effects of pirfenidone (PFD) on the migration, differentiation, and proliferation of retinal pigment epithelial (RPE) cells and demonstrate whether the drug induces cytotoxicity. METHODS: Human RPE cells (line D407) were treated with various concentrations of PFD. Cell mi...

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Detalhes bibliográficos
Main Authors: Wang, Jing, Yang, Yangfan, Xu, Jiangang, Lin, Xianchai, Wu, Kaili, Yu, Minbin
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883732/
https://ncbi.nlm.nih.gov/pubmed/24415895
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