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Accumulation of an Intermediate in DNA Synthesis by HEp.2 Cells Treated with Methyl Methanesulfonate

A portion of the DNA synthesized by HEp.2 cells after short incubation in the presence of BrdU bands in a CsCl gradient at a distinct peak of density 1.715-1.718 g/cm(3). Inhibition of DNA synthesis by methyl methanesulfonate results in an increased proportion of this “intermediate density” DNA. Cel...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kato, Karen, Strauss, B.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1974
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4365578/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.5.1969
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