Mycobacterium tuberculosis Ser/Thr Protein Kinase B Mediates an Oxygen-Dependent Replication Switch

The majority of Mycobacterium tuberculosis (Mtb) infections are clinically latent, characterized by drug tolerance and little or no bacterial replication. Low oxygen tension is a major host factor inducing bacteriostasis, but the molecular mechanisms driving oxygen-dependent replication are poorly u...

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Autors principals: Ortega, Corrie, Liao, Reiling, Anderson, Lindsey N., Rustad, Tige, Ollodart, Anja R., Wright, Aaron T., Sherman, David R., Grundner, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883633/
https://ncbi.nlm.nih.gov/pubmed/24409094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001746
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