An efficient Trojan delivery of tetrandrine by poly(N-vinylpyrrolidone)-block-poly(ε-caprolactone) (PVP-b-PCL) nanoparticles shows enhanced apoptotic induction of lung cancer cells and inhibition of its migration and invasion

Earlier studies have demonstrated the promising antitumor effect of tetrandrine (Tet) against a series of cancers. However, the poor solubility of Tet limits its application, while its hydrophobicity makes Tet a potential model drug for nanodelivery systems. We report on a simple way of preparing dr...

Full description

Saved in:
Bibliographic Details
Main Authors: Xu, Huae, Hou, Zhibo, Zhang, Hao, Kong, Hui, Li, Xiaolin, Wang, Hong, Xie, Weiping
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883593/
https://ncbi.nlm.nih.gov/pubmed/24403829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S55541
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items