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Development and characterization of a gastroretentive dosage form composed of chitosan and hydroxyethyl cellulose for alendronate

In this study, alendronate, the most commonly used biphosphonate for treating osteoporosis, was formulated as gastroretentive dosage form (GRDF) tablets to enhance its oral bioavailability. GRDF tablets were characterized with the effects of different molecular weights (MWs) of chitosan (CS) and hyd...

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Detalhes bibliográficos
Main Authors: Chen, Ying-Chen, Ho, Hsiu-O, Chiu, Chiao-Chi, Sheu, Ming-Thau
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883582/
https://ncbi.nlm.nih.gov/pubmed/24403821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S52791
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