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Distinct signaling pathways regulate TLR2 co-stimulatory function in human T cells

Toll-like receptor 2 (TLR2) serves as a co-stimulatory receptor for human T cells by enhancing T cell receptor (TCR)-induced cytokine production and proliferation. However, it is unknown where signals from the TCR and TLR2 converge to enhance T cell activation. To address this gap, we examined chang...

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Detalhes bibliográficos
Main Authors: Chapman, Nicole M., Bilal, Mahmood Y., Cruz-Orcutt, Noemi, Knudson, Cory, Madinaveitia, Sofia, Light, Jonathan, Houtman, Jon C.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883577/
https://ncbi.nlm.nih.gov/pubmed/23219913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.11.026
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