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Leptin Deficiency Promotes Central Sleep Apnea in Patients With Heart Failure

BACKGROUND: Leptin-deficient animals hyperventilate. Leptin expression by adipocytes is attenuated by atrial natriuretic peptide (ANP). Increased circulating natriuretic peptides (NPs) are associated with an increased risk of central sleep apnea (CSA). This study tested whether serum leptin concentr...

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Detalhes bibliográficos
Main Authors: Cundrle, Ivan, Somers, Virend K., Singh, Prachi, Johnson, Bruce D., Scott, Christopher G., van der Walt, Christelle, Olson, Lyle J.
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883266/
https://ncbi.nlm.nih.gov/pubmed/24030529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.12-2914
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